Yes, there is actually a way (on most machines)

You are loading the IONCube loaders in a local PHP.INI file in your user directories.

The file probably has a "zend_extension=..."  line, pointing to your ION loaders.

What you need to do is modify your php.ini file to look similar to this:

zend_extension=/usr/local/lib/ioncube/ioncube_loader_lin_5.0.so
zend_extension=/usr/local/lib/Zend/ZendOptimizer.so
zend_optimizer.optimization_level=15


The first and seconds lines, need to point to the correct files in the correct paths.  You may have to ask your hosting provider to get the path for the Zend.